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Medchemexpress LLC Suberoyl bis-hydroxamic acid | 38937-66-5 | 95.0% | 204.22 | 100 MG

Supplier: Medchemexpress LLC HYW009776100MG
Suberoyl bis-hydroxamic acid (SBHA) is a competitive and cell-permeable inhibitor targeting HDAC1 and HDAC3, demonstrating ID50 values of 0.25 μM and 0.30 μM, respectively. This compound sensitizes multiple myeloma (MM) cells to apoptosis and activates mitochondrial apoptotic pathways. It is also used in the study of medullary thyroid carcinoma (MTC).
- Inhibits HDAC1 and HDAC3.
- Enhances apoptosis in multiple myeloma cells.
- Facilitates mitochondrial apoptotic pathways.
- Applicable for medullary thyroid carcinoma research.
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