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Apexbio Technology LLC Sulfamerazine 127-79-7 5g
Supplier: Apexbio Technology LLC B20375000
Sulfamerazine (127-79-7) is a small-molecule inhibitor targeting bacterial dihydropteroate synthase It is designed to competitively inhibit this key enzyme thereby disrupting bacterial folate biosynthesis Sulfamerazine exerts its biological activity primarily through competitive inhibition of bacterial dihydropteroate synthase interfering with dihydrofolic acid production and subsequent DNA and RNA biosynthesis in susceptible bacteria In biochemical assays Sulfamerazine demonstrates inhibitory activity with IC50 values typically reported within the micromolar range depending on the bacterial strain and experimental conditions Based on these pharmacological properties Sulfamerazine holds research potential in elucidating antimicrobial resistance mechanisms studying bacterial metabolic pathways and investigating the molecular biology of bacterial folate synthesis
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