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Medchemexpress LLC Sulfo-SPDB-DM4 | 1626359-59-8 | 99.8% | 1075.66 | C46H63ClN4O17S3 | 5 MG
Supplier: Medchemexpress LLC HY1011415MG
sulfo-SPDB-DM4 is a drug-linker conjugate for antibody-drug conjugate (ADC) research that delivers the maytansine-derived cytotoxin DM4 via a cleavable sulfo-SPDB linker. DM4 is an antitubulin maytansinoid that inhibits tubulin polymerization, causing mitotic arrest and apoptotic cell death. The product is supplied as a solid for use in ADC development and related in vitro studies.
- Delivers DM4, a maytansine-derived antitubulin payload, for ADC payload evaluation.
- Cleavable sulfo-SPDB linker enables intracellular release of the cytotoxin.
- High purity (≈99.8%) suitable for research applications.
- Supplied as a solid, white to yellow, shipped on dry ice.
- Soluble in DMSO at 50 MG/ML with ultrasonic assistance; hygroscopic DMSO affects solubility.
- Recommended storage at -80°C, protected from light, under nitrogen.
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