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Enzo Life Sciences Sulindac sulfide (25mg). CAS: 32004-67-4
SDP

Supplier:  Enzo Life Sciences BMLAP2000025

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Active metabolite of sulindac (ALX-430-105). Inhibits cyclooxygenase. More selective for PGHS-1 (ID50=0.5 µM) over PGHS-2 (ID50=14 µM). Induces apoptosis by a cyclooxygenase-independent mechanism. Inhibits colorectal cancer growth and γ-secretase. NF-κB inhibitor. Inhibits Ras signaling. Alternative name: Z-5-Fluoro-2-methyl-1-[p-(methylthio)benzylidene]indene-3-acetic acid. Purity: ≥99% (TLC). Solubility: Soluble in DMSO (>25mg/ml) or 100% ethanol (5mg/ml, warm). Long Term Storage: Ambient.

Catalog No. 50-201-0310


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