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Medchemexpress LLC Sumatriptan succinate (GR 43175 succinate) | 103628-48-4 | 99.9% | 500 MG
SDP

Supplier:  Medchemexpress LLC HYB0121500MG

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Sumatriptan succinate (GR 43175) is an orally active 5-HT1 receptor agonist with IC50s of 7.3 nM, 9.3 nM, and 17.8 nM for 5-HT1D, 5-HT1B, and 5-HT1F receptors, respectively. It can be used for migraine headache research.

  • Orally active 5-HT1 receptor agonist.
  • Targets 5-HT1D, 5-HT1B, and 5-HT1F receptors.
  • Effective in migraine headache research.
  • Demonstrated to reverse nitroglycerin-induced thermal hypersensitivity in mice (600 μg/kg, i.p. or 0.06 μg in 5 μL, i.t.).

Catalog No. 50-004-50902


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