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Enzo Life Sciences SUMO-2 aldehyde (25 µg)
Supplier: Enzo Life Sciences BMLUW00650025
Inhibitor of deSUMOylating enzymes (SENPs). SUMO-2 aldehyde is a highly specific inhibitor of SENP enzymes and has utility in the stabilisation of SUMO-protein conjugates in vitro, enhancing their accumulation in cell lysates and tissue extracts. In addition, co-crystallisation of yeast SUMO (Smt3) aldehyde with the yeast deSUMOylating enzyme Ulp1 has been used to probe the enzyme: substrate interactions, so human SUMO-aldehydes may therefore be of similar utility, and SUMO-2 aldehyde may be used in conjunction with SUMO-1 aldehyde to probe the SUMO paralogue preference of SENP enzymes. Inhibitor of deSUMOylating enzymes (SENPs). SUMO-2 aldehyde is a highly specific inhibitor of SENP enzymes and has utility in the stabilisation of SUMO-protein conjugates in vitro. Alternative name: Sentrin 2 aldehyde. Concentration: 1mg/ml. Purity: ≥95% (HPLC). Formulation: Liquid. In 0.15M HCl. Source: Produced in E. coli cells. Derivatised chemically, in vitro.
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