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Selleck Chemical LLC Sunitinib malate S1042-1g
Supplier: Selleck Chemical LLC S10421G
Sunitinib malate is a multi-targeted RTK inhibitor targeting VEGFR2 (Flk-1) and PDGFR with IC50 of 80 nM and 2 nM in cell-free assays and also inhibits c-Kit Sunitinib Malate effectively inhibits autophosphorylation of Ire1 Sunitinib Malate increases both death receptor and mitochondrial-dependent apoptosis
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