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Medchemexpress LLC SZM679 | 3027645-52-6 | C27H18F5N3O5S | 1 ML
Supplier: Medchemexpress LLC HY15187310MM/1ML
SZM679 is a potent, orally active, and selective RIPK1 inhibitor with Kd values of 8.6 nM for RIPK1. It reverses tumor necrosis factor-induced systemic inflammatory response, decreases Tau hyperphosphorylation, neuroinflammation, and RIPK1 phosphorylation levels. This compound is used in research for Alzheimer's disease (AD) due to its ability to improve cognitive function and rescue brain structural damage.
- Potent, orally active, and selective RIPK1 inhibitor.
- Reverses tumor necrosis factor-induced systemic inflammatory response.
- Decreases Tau hyperphosphorylation, neuroinflammation, and RIPK1 phosphorylation levels.
- Used in research for Alzheimer's disease.
- Inhibits the RIPK1 pathway.
- Protects against necroptosis.
- Improves cognitive function in AD models.
- Rescues brain structure damage and decreases AD biomarkers.
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