Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Medchemexpress LLC SZM679 | 3027645-52-6 | C27H18F5N3O5S | 100 MG
Supplier: Medchemexpress LLC HY151873100MG
SZM679 is a potent, orally active, and selective RIPK1 inhibitor. It reverses tumor necrosis factor-induced systemic inflammatory response and decreases Tau hyperphosphorylation, neuroinflammation, and RIPK1 phosphorylation levels. This compound is valuable for research, particularly in the study of Alzheimer's disease.
- Potent and selective RIPK1 inhibitor (Kd 8.6 nM)
- Reverses TNF-induced systemic inflammatory response
- Decreases Tau hyperphosphorylation and neuroinflammation
- Reduces RIPK1 phosphorylation levels
- Protects against necroptosis
- Inhibits expression of RIPK1 and blocks necrosome formation
- Improves cognitive function and anxiety in AD models
- Rescues brain structure damage
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?