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Medchemexpress LLC Tafamidis meglumine | 951395-08-7 | 99.8% | 503.33 | 5 MG
SDP

Supplier:  Medchemexpress LLC 5MGHY14852A

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Tafamidis meglumine is a potent and selective transthyretin (TTR) stabilizer. It shows comparable potency and efficacy to the mutant homotetramers V30M-TTR, V122I-TTR, and wild type WT-TTR, with EC50s of 2.7-3.2 μM. Tafamidis meglumine inhibits amyloidogenesis.

  • Potent and selective transthyretin (TTR) stabilizer
  • Inhibits amyloidogenesis
  • Comparable potency and efficacy to mutant homotetramers V30M-TTR, V122I-TTR, and wild type WT-TTR
  • Binds selectively to thyroxine-binding sites of the tetramer
  • Kinetically stabilizes TTR

Catalog No. 50-003-64330


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