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Medchemexpress LLC Taltirelin acetate | 1549593-23-8 | 99.4% | 100 MG
Supplier: Medchemexpress LLC HYB0596A100MG
Taltirelin acetate is an acetate form of Taltirelin (TA-0910), an orally effective analogue of thyrotropin releasing hormone (TRH). It acts as a TRH receptor superagonist and can cross the blood-brain barrier. Taltirelin acetate stimulates an increase in cytosolic Ca2+ concentration and exhibits neuroprotective effects in cellular and animal models of Parkinson's disease, also alleviating fatigue-like behavior in mouse models of cancer-related fatigue.
- Orally effective analogue of thyrotropin releasing hormone (TRH)
- TRH receptor superagonist
- Crosses the blood-brain barrier
- Stimulates increase in cytosolic Ca2+ concentration
- Neuroprotective effects in Parkinson's disease models
- Alleviates fatigue-like behavior in cancer-related fatigue models
- Increases cell viability and reduces apoptosis in SH-SY5Y cells
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