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Medchemexpress LLC Taltirelin acetate (TA-0910 acetate) | 1549593-23-8 | 99.4% | 50 MG
Supplier: Medchemexpress LLC HYB0596A50MG
Taltirelin acetate (TA-0910 acetate) is an acetate form of Taltirelin (TA-0910), an orally effective analogue of thyrotropin releasing hormone (TRH) and a TRH receptor (TRH-R) superagonist. This compound can cross the blood-brain barrier and stimulates an increase in cytosolic Ca2+ concentration.
- Orally effective analogue of thyrotropin releasing hormone (TRH)
- TRH receptor (TRH-R) superagonist
- Can cross the blood-brain barrier
- Stimulates an increase in cytosolic Ca2+ concentration (Ca2+ release)
- Increases cell viability and reduces apoptosis in SH-SY5Y cells and primary rat mesencephalic neurons
- Demonstrates neuroprotective effects in cellular and animal models of Parkinson's disease
- Alleviates fatigue-like behavior in mouse models of cancer-related fatigue
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