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Medchemexpress LLC Taraxerone | 514-07-8 | 424.70 | 5 MG
Supplier: Medchemexpress LLC HYN11775MG
Taraxerone is isolated from Sedum sarmentosum and enhances effects on alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase (ALDH) activities with EC50 values of 512.42 and 500.16 μM, respectively. It significantly lowers plasma alcohol and acetaldehyde concentrations in mice and prevents decreases in catalase, superoxide dismutase, and reduced glutathione concentrations induced by ethanol administration.
- Enhances alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase (ALDH) activities.
- Significantly lowers plasma alcohol and acetaldehyde concentrations in mice.
- Increases ADH and ALDH expressions in liver tissues after ethanol exposure.
- Prevents decreases in catalase, superoxide dismutase, and reduced glutathione concentrations induced by ethanol administration.
- Target: Aldehyde dehydrogenase (ALDH).
- Pathway: Metabolic enzyme/protease.
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