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Cayman Chemical TAS 103hydrochlorIde 50mg
SDP

Supplier:  Cayman Chemical 2986950 MG

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A CXCR4 antagonist (IC50 13 nM in a radioligand binding assay) selective for CXCR4 over CCR1 CCR2b CCR4 CCR5 CXCR1 and CXCR2 (IC50s 10 UM for all) reduces CXCL12-induced chemotaxis of CCRF-CEM T cells (IC50 19 nM) inhibits fusion of CHO-K1 cells expressing gp120 to P4 MAGI cells IC50 1 5 nM decreases HIV-1 NL4 3 viral replication in MT-4 cells and isolated human PBMCs (IC50s 2 and 9 nM respectively)

Catalog No. 50-298-9186


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