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Medchemexpress LLC Tat-cyclo-cllfvy | 1446322-66-2 | 98.8% | 2559.08 | 1 MG
Supplier: Medchemexpress LLC HYP14201MG
TAT-cyclo-CLLFVY is a cyclic peptide inhibitor of HIF-1 heterodimerization that inhibits hypoxia signaling in cancer cells. It disrupts HIF-1α/HIF-1β protein-protein interaction with an IC50 of 1.3 μM.
- Cyclic peptide inhibitor of HIF-1 heterodimerization
- Inhibits hypoxia signaling in cancer cells
- Disrupts HIF-1α/HIF-1β protein-protein interaction
- Inhibits HIF-1 activity in mammalian cell luciferase reporter assay
- Powder storage: -80°C for 2 years, -20°C for 1 year
- In solvent storage: -80°C for 6 months, -20°C for 1 month
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