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Medchemexpress LLC TAT-cyclo-CLLFVY | 1446322-66-2 | 98.8% | 2559.08 | 10 MG
Supplier: Medchemexpress LLC HYP142010MG
TAT-cyclo-CLLFVY is a cyclic peptide inhibitor of HIF-1 heterodimerization, effectively inhibiting hypoxia signaling in cancer cells. It functions by disrupting the HIF-1α/HIF-1β protein-protein interaction. This product is for research use only.
- Disrupts HIF-1α/HIF-1β protein-protein interaction with an IC50 of 1.3 μM
- Inhibits HIF-1 activity in mammalian cell luciferase reporter assay with an IC50 of 19±2 μM
- Shows similar inhibition in MCF-7 breast cancer cells with an IC50 of 16±1 μM
- Features a molecular weight of 2559.08
- Has a chemical formula of C111H188N42O24S2
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