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Medchemexpress LLC TAT-cyclo-CLLFVY | 1446322-66-2 | 98.8% | 2559.08 | 5 MG
SDP

Supplier:  Medchemexpress LLC HYP14205MG

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TAT-cyclo-CLLFVY is a cyclic peptide inhibitor of HIF-1 heterodimerization that inhibits hypoxia signaling in cancer cells. It disrupts HIF-1α/HIF-1β protein-protein interaction with an IC50 of 1.3 μM and inhibits HIF-1 activity in mammalian cell luciferase reporter assays with IC50 values of 19±2 μM (hypoxia) and 16±1 μΜ (MCF-7 breast cancer cells).

  • Disrupts HIF-1α/HIF-1β protein-protein interaction
  • Inhibits hypoxia signaling in cancer cells
  • Inhibits HIF-1 activity in mammalian cell luciferase reporter assays
  • For research use only

Catalog No. 50-004-22600


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