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Apexbio Technology LLC Taurolithocholic Acid MaxSpec Standard 516-90-5 100ug
Supplier: Apexbio Technology LLC A90760.1
Taurolithocholic Acid MaxSpec Standard (CAS 516-90-5) is a taurine-conjugated form of lithocholic acid classified as a secondary bile acid In cellular models taurolithocholic acid (TLCA) has been shown to elevate caspase-3 and caspase-7 activities in Hep3B cells expressing the sodium-taurocholate cotransporting polypeptide (NTCP) without affecting untransfected cells TLCA is also employed to induce cholestasis in ex vivo and in vivo liver models for the investigation of hepatobiliary function and toxicity Additionally its serum levels increase significantly following oral lipid tolerance tests in humans The MaxSpec Standard is quality-controlled for mass spectrometry-based quantitative assays
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