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Medchemexpress LLC TCO-PEG12-NHS ester | 2185016-39-9 | MFCD00012569 | 95.0% | 866.99 | C40H70N2O18 | 10 MG
SDP

Supplier:  Medchemexpress LLC HY14117010MG

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TCO-PEG12-NHS ester is a PEG-based linker reagent consisting of a trans-cyclooctene (TCO) group connected through a 12-unit polyethylene glycol (PEG12) spacer to an N-hydroxysuccinimide (NHS) ester. It enables efficient amine coupling and rapid tetrazine click chemistry, and is used as a cleavable linker in ADC and PROTAC synthesis for bioconjugation applications.

  • Provides a TCO functional group for rapid click reactions.
  • PEG12 spacer improves solubility and reduces steric hindrance.
  • NHS ester enables efficient coupling to primary amines.
  • Suitable for ADC and PROTAC linker construction and general bioconjugation.
  • Supplied in small research-scale quantities for conjugation workflows.

Catalog No. 50-002-03765


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