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Cayman Chemical tcYNH2trIfluoroACTAte sal 10mg
Supplier: Cayman Chemical 3675810 MG
A peptide antagonist of PAR4; inhibits platelet aggregation induced by AYPGKF-NH2 in washed isolated rat platelets (IC50 = 95-190 µM); induces relaxation of isolated rat aortic rings precontracted with phenylephrine and contraction of isolated rat gastric longitudinal muscle strips (EC50s = 64 and 1 µM, respectively); inhibits thrombin-induced migration of primary HCC cells at 400 µM; reduces myocardial infarct size as a percentage of the area at risk ex vivo in an isolated rat heart model of ischemia-reperfusion injury
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