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Medchemexpress LLC Tebanicline dihydrochloride | 209326-19-2 | 99.49% | C9H13Cl3N2O | 100 MG
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Supplier:  Medchemexpress LLC HY14316A100MG

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Tebanicline dihydrochloride is an nAChR modulator with potent, orally effective analgesic activity. It inhibits the binding of cytisine to α4β2 neuronal nAChRs with a Ki of 37 pM. This compound shows preferential selectivity for neuronal nAChRs and acts as an agonist.

  • Potent, orally effective analgesic activity.
  • Inhibits binding of cytisine to α4β2 neuronal nAChRs.
  • Selective for neuronal nAChRs.
  • Agonist at transfected human α4β2 neuronal nAChR.
  • Produces antinociceptive effects in models of acute and persistent pain.
  • Effective against acute noxious thermal stimulation.
  • Antinociceptive in rat models of acute thermal, persistent chemical, and neuropathic pain.

Catalog No. 50-003-56684


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