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Medchemexpress LLC Telotristat ethyl | 1033805-22-9 | 98.9% | 100 MG
Supplier: Medchemexpress LLC HY13055A100MG
Telotristat ethyl is a novel, orally-delivered inhibitor of tryptophan hydroxylase that reduces serotonin production. It is intended for research use only.
- Reduces serotonin content in the periphery.
- Prevents increase in blood neutrophil counts after TNBS challenge.
- Provides significant protection in a mouse model of inflammatory bowel disease.
- Protects mouse IBD model, confirmed by histopathology evaluation.
- Depletes 5-HT from the jejunum.
- Alleviates the severity of trinitrobenzene sulfonic acid (TNBS)-induced colitis.
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