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Selleck Chemical LLCSupplier Diversity Partner Temozolomide 25mg 85622-93-1 CCRG81045, NSC 362856,TMZ  DFS Item

Manufacturer:  Selleck Chemical LLCSupplier Diversity Partner S123725MG

Temozolomide (CCRG81045, NSC 362856, TMZ) is a monofunctional SN-1 alkylating agent that can modify nitrogen atoms in the DNA ring and the extracyclic oxygen group, chemically converted to MTIC and degrades to methyldiazonium cation, which transfers methyl groups to DNA at physiologic pH. A DNA damage inducer in L-1210 and L-1210/BCNU cells. Temozolomide induces apoptosis and exhibits antitumor activity.

Catalog No. 50-711-6


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