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Apexbio Technology LLC Teniposide 29767-20-2 50mg
Supplier: Apexbio Technology LLC A853250
Teniposide (CAS 29767-20-2) is a semisynthetic glycosidic derivative of podophyllotoxin that functions as a potent inhibitor of DNA topoisomerase II By stabilizing the cleavage complex formed between topoisomerase II and DNA teniposide interrupts the religation step of the DNA strand passage reaction resulting in the accumulation of double-strand breaks and subsequent induction of apoptosis in proliferating cells This compound is widely utilized in biomedical research to investigate mechanisms of DNA damage response cell cycle regulation and apoptotic pathways in various cancer and cell biology models
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