Medchemexpress LLC Tenofovir alafenamide fumarate (GS-7340 fumarate) | 379270-38-9 | C25H33N6O9P | 1 ML

Supplier:  Medchemexpress LLC HY15232A10MM/1ML

Tenofovir alafenamide fumarate is an investigational oral prodrug of Tenofovir, functioning as an HIV-1 nucleotide reverse transcriptase inhibitor. It is intended solely for research purposes and not for patient use.

• Exhibits antiviral activities ranging from 5 to 7 nM
• Effective against a panel of HIV-1 and HIV-2 isolates
• Mean EC50 of 3.5 nM against primary HIV-1 isolates in PBMCs
• Mean EC50 of 1.8 nM for HIV-2 isolates
• Amidate prodrug designed for improved oral bioavailability
• Offers increased plasma stability compared to Tenofovir disoproxil fumarate (TDF)
• High purity of 99.87%
• Appears as a white to off-white solid
• Soluble in DMSO (≥ 36 mg/mL) and H2O (≥ 25 mg/mL)
• Store solid form at 4°C, sealed and away from moisture
• Store solvent form at -80°C for 6 months or -20°C for 1 month

Catalog No. 50-003-73184