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Apexbio Technology LLC Tenofovir hydrate 206184-49-8 10mg

Supplier: Apexbio Technology LLC B125210
Tenofovir hydrate (CAS 206184-49-8) is a small-molecule inhibitor targeting HIV-1 reverse transcriptase It is designed to competitively inhibit reverse transcriptase thereby blocking viral DNA synthesis and replication Tenofovir hydrate exerts its biological activity primarily through intracellular phosphorylation and subsequent inhibition of HIV-1 reverse transcriptase In in vitro studies Tenofovir hydrate demonstrates inhibitory activity with reported EC50 values ranging from 29 fmol per 10 6 cells at low viral input (MOI 1) to 411 fmol per 10 6 cells at higher inputs (MOI 100) Based on these pharmacological properties Tenofovir hydrate holds research potential in the study of viral therapy resistance mechanisms and prophylactic intervention concerning HIV-1 and HBV infections
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