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Medchemexpress LLC Tepotinib | 1100598-32-0 | 99.9% | 492.57 | 50 MG

Supplier: Medchemexpress LLC HY1472150MG
Tepotinib is an orally active, highly selective, reversible, and ATP-competitive inhibitor of c-Met with an IC50 of 3 nM. It demonstrates over 200-fold selectivity for c-Met compared to IRAK4, TrkA, Axl, IRAK1, and Mer. This compound inhibits c-Met phosphorylation and induces autophagy, exhibiting antitumor effects.
- Orally active
- Highly selective c-Met inhibitor
- Reversible and ATP-competitive mechanism
- Inhibits c-Met phosphorylation
- Induces autophagy
- Demonstrates antitumor effects
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