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Medchemexpress LLC Tetrahydrouridine | 18771-50-1 | C9H16N2O6 | 50 MG
Supplier: Medchemexpress LLC HY15345A50MG
Tetrahydrouridine dihydrate is a potent inhibitor of cytidine deaminase (CDA), which competitively blocks the enzyme's active site more effectively than intrinsic cytidine. It is for research use only. Tetrahydrouridine (THU) is a specific inhibitor of cytidine deaminase (CDA) that can suppress deamination in the catabolism of cytotoxic deoxycytidine analogues.
- Competitively blocks the enzyme's active site more effectively than intrinsic cytidine
- Can sensitize some pancreatic and lung carcinoma cells to gemcitabine-induced cell death
- Inhibits S-phase without inducing apoptosis
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