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Medchemexpress LLC Thalidomide-O-amido-PEG2-C2-NH2 (TFA) | 1957235-75-4 | 576.48 | 25 MG
Supplier: Medchemexpress LLC 25MGHY112617A
Thalidomide-O-amido-PEG2-C2-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide-based cereblon ligand and 2-unit PEG linker used in PROTAC technology. PROTACs contain two different ligands connected by a linker, one for an E3 ubiquitin ligase and the other for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- E3 ligase ligand-linker conjugate
- Incorporates thalidomide-based cereblon ligand
- 2-unit PEG linker
- Used in PROTAC technology
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
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