Cayman Chemical TheaflavIn 3 3-dIgalate 10mg

Supplier:  Cayman Chemical 2521510 MG

A polyphenol with diverse biological activities; inhibits the formation of superoxide radicals, singlet oxygen, hydrogen peroxide, and hydroxyl radicals in vitro (IC50s = 26.7, 0.83, 0.39, and 25.07 µmol/L, respectively); reduces hydroxyl radical-induced damage to plasmid DNA; prevents LPS-induced release of TNF-α, IL-1β, and IL-6, expression of JNK and p38, and nuclear translocation of NF-κB in RAW 264.7 cells from 12.5-50 µM; reduces serum levels of TNF-α, IL-1β, and IL-6 and decreases pulmonary edema, pulmonary congestion, and thickening of the alveolar wall in a mouse model of LPS-induced acute lung injury; inhibits osteoclast formation, polarization, and osteoclastic bone resorption in vitro; reduces titanium particle-induced bone erosion and the number of mature osteoclasts in mice

Catalog No. 50-293-4423