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Bachem Mca-(Asn670,Leu671)-Amyloid Beta/A4 Protein Precursor770 (667-676)-Lys(Dnp)-Arg-Arg amide Trifluoroacetate
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Supplier:  Bachem 4033760.0001

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Mca-(Asn670,Leu671)-Amyloid Beta/A4 Protein Precursor770 (667-676)-Lys(Dnp)-Arg-Arg amide Trifluoroacetate, Mca-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Arg-Lys(Dnp)-Arg-Arg-NH2, 438625-61-7, C86H125N27O29, Mr 2001.10, 1mg. Mca-(Asn670,Leu671)-APP770 (667-676)-Lys(Dnp)-Arg-Arg amide. This fluorescent (FRET) peptide substrate contains the 'Swedish' Lys-Met/Asn-Leu mutation of the amyloid precursor protein (APP) b-secretase cleavage site. Mca-SEVNLDAEFRK(Dnp)RR-amide has been used for assaying b-secretase-like activity of thimet oligopeptidase (TOP, EC 3.4.24.15). The results suggested that TOP is a potential b-secretase candidate and is involved in the processing of APP in vivo.

Catalog No. 50-194-6613


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