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Medchemexpress LLC Tinengotinib | 2230490-29-4 | >98.0% | 394.86 g/mol | C20H19ClN6O | 5 MG
SDP

Supplier:  Medchemexpress LLC HY1456015MG

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Tinengotinib is an orally active small-molecule multi-kinase inhibitor used in preclinical oncology research. It potently inhibits Aurora A/B and FGFR family kinases, and also shows activity against VEGFRs, JAK1/2, and CSF1R. By blocking Aurora kinase-mediated cell cycle progression, it induces G2/M arrest, promotes apoptosis, and inhibits proliferation and angiogenesis. It is applied in studies of triple-negative breast cancer, gallbladder cancer, and tumor immune microenvironment. For research use only.

  • Orally active small-molecule kinase inhibitor.
  • Potent multi-kinase activity including Aurora A/B and FGFR1-3.
  • Induces G2/M cell cycle arrest and apoptosis.
  • Demonstrates anti-proliferative and anti-angiogenic effects in preclinical models.
  • Available as solid and DMSO solution formats for flexible dosing.
  • Reported purity >98% and molecular weight 394.86 g/mol.
  • Intended for preclinical research use only.

Catalog No. 50-002-21123


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