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Apexbio Technology LLC Tinidazole 19387-91-8 10mM (in 1mL DMSO)
Supplier: Apexbio Technology LLC B20505.1
Tinidazole is a synthetic nitroimidazole derivative with antiparasitic and antibacterial activity used to study protozoal infections and anaerobic bacterial conditions After cellular uptake it is activated by nitroreductase enzymes forming cytotoxic metabolites that induce DNA strand breaks and inhibit nucleic acid synthesis leading to cell death Tinidazole is commonly used in vitro to evaluate its efficacy against pathogens like Giardia lamblia Trichomonas vaginalis and Entamoeba histolytica IC50 values against Giardia lamblia trophozoites typically range from 0 5 to 5 M making it a useful tool for antiparasitic drug screening and antimicrobial studies
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