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Medchemexpress LLC Tiplaxtinin | 393105-53-8 | C24H16F3NO4 | 10 MM 1 ML
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Supplier:  Medchemexpress LLC HY1525310MM/1ML

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Tiplaxtinin is a selective and orally efficacious inhibitor of plasminogen activator inhibitor-1 (PAI-1) with an IC50 of 2.7 μM.

  • Selective and orally efficacious inhibitor of PAI-1.
  • IC50 of 2.7 μM for PAI-1.
  • Inhibits cellular proliferation in T24 cells and UM-UC-14 cells.
  • Reduces thrombus weight in a rat model of thrombosis.
  • Reduces subcutaneous tumor growth in human bladder cancer and human cervical cancer xenografts.

Catalog No. 50-003-72913


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