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Apexbio Technology LLC Tofacitinib (CP-690550,Tasocitinib) 477600-75-2 50mg
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Supplier:  Apexbio Technology LLC A413850

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Tofacitinib (CP-690550 Tasocitinib CAS 477600-75-2) is an orally bioavailable Janus kinase (JAK) inhibitor employed as a targeted immunomodulator The compound preferentially inhibits signaling mediated by JAK1 and JAK3 heterodimers displaying functional selectivity and less pronounced effects on JAK2 pathways Such inhibition disrupts downstream cytokine signaling notably IL-2 IL-4 IL-7 IL-9 IL-15 and IL-21 cytokines implicated in lymphocyte activation proliferation and differentiation Recent studies also indicate suppression of STAT signaling and potential modulation of additional kinase targets Tofacitinib is broadly studied in autoimmune research especially in rheumatoid arthritis and ulcerative colitis models

Catalog No. 50-000-62639


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