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Selleck Chemical LLC Tofacitinib (CP-690550) 100mg 477600-75-2 Tasocitinib
Supplier: Selleck Chemical LLC S2789100MG
Tofacitinib (CP-690550,Tasocitinib) is a novel inhibitor of JAK3 with IC50 of 1 nM in cell-free assays, 20- to 100-fold less potent against JAK2 and JAK1. Tofacitinib inhibits the expression of antiapoptotic BCL-A1 and BCL-XL in human plasmacytoid dendritic cells (PDC) and induced PDC apoptosis. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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