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Selleck Chemical LLC Tolinapant
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Supplier:  Selleck Chemical LLC S86811MG

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Tolinapant (ASTX660) is a potent non-peptidomimetic antagonist of cIAP1/2 and XIAP that inhibits the interactions between a SMAC-derived peptide and the BIR3 domains of XIAP (BIR3-XIAP) and cIAP1 (BIR3-cIAP1) with IC50 values less than 40 and 12 nmol/L respectively

Catalog No. 50-217-3380


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