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Medchemexpress LLC Tomatidine hydrochloride | 6192-62-7 | 100 MG
Supplier: Medchemexpress LLC HYN2149A100MG
Tomatidine hydrochloride is an anti-inflammatory agent that blocks NF-κB and JNK signaling pathways. It also activates autophagy in mammal cells and C. elegans. In vitro, it decreases inducible NO synthase and COX-2 expression by suppressing I-κBα phosphorylation, NF-κB nuclear translocation, and JNK activation.
- Blocks NF-κB and JNK signaling.
- Activates autophagy in mammal cells and C. elegans.
- Decreases inducible NO synthase and COX-2 expression.
- Suppresses I-κBα phosphorylation.
- Inhibits NF-κB nuclear translocation.
- Inhibits JNK activation.
- Causes dose-dependent inhibition of LPS-induced iNOS expression.
- Suppresses NF-κB binding activity.
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