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Cayman Chemical TopotecnhydrochlorIde 10mg
Supplier: Cayman Chemical 1412910 MG
An inhibitor of DNA topoisomerase I and a derivative of camptothecin; inhibits DNA topoisomerase I in human MCF-7 breast and DU-145 prostate cancer cells (IC50s = 13 and 2 nM, respectively); induces cytotoxicity and DNA damage in HT-29 human colon adenocarcinoma cells (IC50s = 33 and 280 nM, respectively)
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