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Medchemexpress LLC Torin 2 | 1223001-51-1 | 99.65% | 1 ML
Supplier: Medchemexpress LLC HY1300210MM/1ML
Torin 2 is an mTOR inhibitor with an EC50 of 0.25 nM for inhibiting cellular mTOR activity. It exhibits 800-fold selectivity over PI3K (EC50: 200 nM) and also inhibits DNA-PK with an IC50 of 0.5 nM in the cell-free assay. Torin 2 can suppress both mTORC1 and mTORC2.
- Potent mTOR inhibitor with an EC50 of 0.25 nM for cellular mTOR activity.
- Exhibits 800-fold selectivity over PI3K.
- Inhibits DNA-PK with an IC50 of 0.5 nM in cell-free assays.
- Suppresses both mTORC1 and mTORC2.
- Demonstrates good bioavailability and exposure in vivo.
- Possesses improved pharmacokinetic properties for in vivo experiments.
- Maintains strong inhibition of mTOR activity in lung and liver for extended periods.
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