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Medchemexpress LLC Trans-nerolidol | 40716-66-3 | 100 MG
Supplier: Medchemexpress LLC HYN6635100MG
Trans-Nerolidol enhances the anti-proliferative effects of Doxorubicin (DOX) against various cancer cells, including intestinal and breast cancer cells, by increasing DOX accumulation inside cells and activating apoptosis. It exhibits synergistic effects in some breast cancer cell lines and can inhibit cell migration.
- Increases accumulation of Doxorubicin (DOX) inside cells.
- Activates apoptosis in vivo.
- Inhibits cell migration.
- Suppresses phosphor-FAK (Tyr397) expression.
- Elevates CD44 expression when combined with DOX.
- Increases the phosphorylated form of p53 in mice with EST cancer cells.
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