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Apexbio Technology LLC TRAP-6 141136-83-6 10mg
Supplier: Apexbio Technology LLC A867510
TRAP-6 (CAS 141136-83-6) is a synthetic hexapeptide corresponding to residues 42 47 of the protease-activated receptor 1 (PAR1) Functioning as a selective PAR1 agonist TRAP-6 activates the receptor to stimulate platelet aggregation with an EC50 of 0 8 M Upon PAR1 activation TRAP-6 induces intracellular Ca2 mobilization and triggers rapid phosphorylation of phosphodiesterase 3A (PDE3A) This compound is widely employed in biomedical research to investigate platelet signaling pathways receptor-mediated cellular responses and the molecular mechanisms underlying thrombotic processes
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