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Medchemexpress LLC TRF1-TIN2 PPI-IN-1 | 374.41 | 5 MG
Supplier: Medchemexpress LLC HY1726625MG
TRF1-TIN2 PPI-IN-1 is an inhibitor of the TRF1-TIN2 interaction. It binds to the TRFH domain of TRF1 and competitively inhibits the binding of the TIN2 peptide. This compound disrupts the interaction between TRF1 and TIN2 by occupying the hotspot region of the binding interface. It can expel TRF1 from the shelterin complex.
- Disrupts TRF1-TIN2 interaction
- Binds to TRFH domain of TRF1
- Competitively inhibits TIN2 peptide binding
- Can be used to study shelterin-related cancers
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