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Apexbio Technology LLC Triamcinolone 124-94-7 10mM (in 1mL DMSO)
Supplier: Apexbio Technology LLC B18595.1
Triamcinolone (124-94-7) is a small-molecule agonist targeting intracellular glucocorticoid receptors (GR) It is designed to modulate the transcriptional regulation of genes involved in inflammation immune responses cellular proliferation vascular permeability and angiogenesis thereby regulating multiple cellular and immunological pathways Triamcinolone exerts its biological activity primarily through binding to GR and modulating downstream gene expression In cell-based GR assays Triamcinolone demonstrates potent receptor binding with reported IC50 values typically ranging from 0 5 to 5 nM Based on these pharmacological properties Triamcinolone holds research potential in experimental models of dermatological inflammation ophthalmic inflammation autoimmune conditions and investigations of GR-mediated signal transduction and immunoregulatory pathways
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