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Cayman Chemical TrIcIrIbIn Phosphate 10mg
Supplier: Cayman Chemical 3798510 MG
An Akt activation inhibitor and active metabolite of triciribine; binds to the PH domain of Akt and prevents its recruitment to the plasma membrane in MDA-MB-468 cells; reduces the proliferation of A1847 and A2780 cells (IC50s = 1.6 and 18 µM, respectively); inhibits HIV-1 reverse transcriptase activity in CEM-SS cells (IC50 = 0.04 µM), as well as HSV-1 replication in BS-C-1 cells and human CMV plaque formation in HFF-1 IRR cells (IC50s = 20 and 0.8 µM, respectively)
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