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Medchemexpress LLC Triciribine (API-2) | 35943-35-2 | C13H16N6O4 | 1 ML
Supplier: Medchemexpress LLC HY1545710MM/1ML
Triciribine is a nucleoside analog and purine analog that acts as a DNA synthesis inhibitor. It also selectively inhibits the phosphorylation and activation of all three Akt isoforms, with IC50 values of 130 nM for Akt and 0.02-0.46 μM for HIV-1/2. This product is for research use only.
- Inhibits DNA synthesis
- Inhibits Akt with an IC50 of 130 nM (cell assay)
- Inhibits HIV-1 and HIV-2 with IC50 values of 0.02-0.46 μM
- Selectively inhibits phosphorylation and activation of all three Akt isoforms
- Inhibits Akt phosphorylation at Thr308 and Ser473 at 10 μM concentration
- Effectively inhibits phosphorylation and catalytic activity of Akt in PC-3 cells
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