Apexbio Technology LLC Trimethobenzamide hydrochloride 554-92-7 500mg

Supplier:  Apexbio Technology LLC C6974500

Trimethobenzamide hydrochloride is a dopamine D2 receptor antagonist frequently utilized in biomedical research investigating mechanisms underlying emesis and anti-emetic responses The compound exerts pharmacological effects by inhibiting dopamine receptor-mediated neurotransmission within the chemoreceptor trigger zone (CTZ) of the central nervous system a key regulatory area implicated in nausea and vomiting reflexes Through selective receptor blockade trimethobenzamide hydrochloride allows researchers to elucidate dopamine-dependent molecular and physiological pathways contributing to vomiting in experimental animal models This compound is commonly applied in laboratory settings to characterize the pharmacodynamic profiles of novel anti-emetic agents and to evaluate dopamine receptor-involved emetic signaling The reported IC50 value for dopamine D2 receptor inhibition is approximately 320 nM

Catalog No. 50-000-64060