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Medchemexpress LLC Trimethyl chitosan (N,N,N-trimethylchitosan) | 52349-26-5 | 100 MG

Supplier: Medchemexpress LLC HY148033100MG
Trimethyl chitosan (N,N,N-Trimethylchitosan) is a multifunctional polymer derived from Chitosan, enhancing absorption by targeting tight junction proteins in intestinal and mucosal epithelial cells. This leads to protein rearrangement and increased intercellular permeability, stimulating transmembrane transport of hydrophilic drugs like peptides and proteins for drug delivery and nanoparticle synthesis.
- Multifunctional polymer.
- Targets absorption enhancing proteins of tight junctions.
- Induces tight junction protein rearrangement and increases intercellular permeability.
- Stimulates transmembrane transport of hydrophilic drugs (e.g., peptides and proteins).
- Used for drug delivery and synthesis of nanoparticles.
- In Caco-2 cell monolayer experiments, it reduced transepithelial electrical resistance (TEER) and increased 14C-mannitol transport without affecting cell viability.
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