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Cayman Chemical TrImethylamIn N-oxIde 500mg
Supplier: Cayman Chemical 17354500 MG
A metabolite of choline, phosphatidylcholine, and L-carnitine; dietary administration increases renal tubulointerstitial fibrosis, collagen deposition, and Smad3 phosphorylation in mice and increases aortic lesion area in atherosclerosis-prone ApoE-/- mice at 0.12% w/w; plasma levels of TMAO are elevated in patients with chronic kidney disease and decreased in patients with active, compared with inactive, ulcerative colitis; elevated plasma levels of TMAO are associated with increased risk of cardiovascular disease
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