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Medchemexpress LLC Tryptamine guanosine carbamate | 1414808-96-0 | 99.79% | 469.45 | 50 MG
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Supplier:  Medchemexpress LLC HY13888550MG

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Tryptamine guanosine carbamate (TpGc) is a selective HINT1 (histidine triad nucleotide-binding protein 1) inhibitor with a Ki of 34 μM and Kd of 3.65 μM. It significantly enhances morphine antinociception and prevents the development of tolerance.

  • Selective HINT1 inhibitor
  • Enhances morphine antinociception
  • Prevents the development of tolerance to morphine
  • Reduces the recruitment of NMDAR activity promoted by morphine
  • Attenuates NMDAR function and alleviates mechanical allodynia in mice with chronic constriction injury

Catalog No. 50-003-50504


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